Course Schedule
Training in Neurotherapeutics Discovery and Development for Academic Scientists
TUESDAY, MARCH 25, 2025
|
8:00
— 8:30 am |
Continental
Breakfast |
All
participants |
Vanderhoef
Theatre Lobby, Mondavi Center |
|
8:00
— 8:30 am |
Registration
& badge pickup |
All
participants |
Vanderhoef
Theatre Lobby, Mondavi Center |
|
8:30
—9:20 am |
Session
1: Overview: The Neurotherapeutics Discovery and Development Process |
Michael A. Rogawski, M.D., Ph.D., University of California,
Davis |
Vanderhoef
Theatre, Mondavi Center |
|
9:20
— 10:10 am |
Session
2: Moving From Hit to Lead to Clinical Candidate |
James
Barrow, Ph.D., Johns Hopkins School of Medicine |
Vanderhoef
Theatre, Mondavi Center |
|
10:10
— 10:30 am |
BREAK |
||
|
10:30
— 11:20 am |
Session
3: ADME |
Kennan
Marsh, Ph.D., AbbVie |
Vanderhoef
Theatre, Mondavi Center |
|
11:20
am — 12:10 pm |
Session
4: Toxicology |
Ruokun
Wang, Ph.D., DABT |
Vanderhoef
Theatre, Mondavi Center |
|
12:10
— 12:15 pm |
Introduction
to Engagement Exercises |
Course
Directors |
Vanderhoef
Theatre, Mondavi Center |
|
12:15
— 1:40 pm |
Lunch & Engagement Exercise 1: Mentor Teams Meeting For team assignments: see
Mentor Teams handout or course website |
Mentor
Teams |
Mondavi
Center, 3rd fl. |
|
1:40
— 2:30 pm |
Session
5: Animal Models |
Gregory
Carr, Ph.D., Johns Hopkins School of Medicine |
Vanderhoef
Theatre, Mondavi Center |
|
2:30
— 3:20 pm |
Session
6: Formulation and Routes of Administration |
Maureen Donovan, Ph.D., University of Iowa |
Vanderhoef
Theatre, Mondavi Center |
|
3:20
— 3:25 pm |
Introduction
to Round Robins |
Course
Directors |
Vanderhoef
Theatre, Mondavi Center |
|
3:25
— 3:50 pm |
Break/Transition
to Round Robins |
||
|
3:50
— 5:00 pm |
Engagement
Exercise 2: Round Robins (See Round Robins schedule handout on website) |
Mentor
Teams |
Mondavi
Center, 3rd fl. |
|
3:50
— 4:20 pm |
Rotation 2 |
||
|
4:30
— 5:00 pm |
Rotation 3 |
||
|
5:00
— 6:00 pm |
BREAK |
||
|
6:00
— 8:00 pm |
Dinner |
All
invited |
Vanderhoef
Theatre, Mondavi Center |
|
|
Special
Guest Lecture: RNA-Targeted Therapies for Neurodegenerative Disease |
Timothy
Miller, M.D., Ph.D., Washington University in St. Louis |
|
WEDNESDAY, MARCH 26, 2025
|
8:00
— 8:30 am |
Continental
Breakfast |
All
participants |
Vanderhoef
Theatre Lobby, Mondavi Center |
|
8:30
— 8:35 am |
Welcome
& Daily Overview |
Course
Directors |
Vanderhoef
Theatre, Mondavi Center |
|
8:35
— 9:25 am |
Session
7: Alternative Routes of Administration |
James Cloyd, Pharm.D., University of Minnesota |
Vanderhoef
Theatre, Mondavi Center |
|
9:25—
10:30 am |
Session
8:
Adeno-associated
virus (AAV) Gene Therapies and Small Interfering RNA (siRNA) Therapeutics |
Dinah
Sah, Ph.D. |
Vanderhoef
Theatre, Mondavi Center |
|
10:30
— 10:50 am |
BREAK |
||
|
10:50
— 11:40 am |
Session
9: Antisense Oligonucleotides |
Gene
Liau, Ph.D., Adagen Preclinical Solutions and Tacit Therapeutics |
Vanderhoef
Theatre, Mondavi Center |
|
11:40
am —12:30 pm |
Session
10:
Antibody Therapies |
Gai
Ayalon, Ph.D., FOXG1 Research Foundation |
Vanderhoef
Theatre, Mondavi Center |
|
12:30
— 2:00 pm |
Lunch
& Responsible Conduct of Research Exercise 1 |
Mentor
Teams |
Mondavi
Center, 3rd fl. |
|
2:00
— 2:50 pm |
Session
11:
Rigor in Translational
Drug Discovery and Development |
Shai
Silberberg, Ph.D., National Institute of Neurological Disorders and Stroke
(NINDS) |
Vanderhoef
Theatre, Mondavi Center |
|
2:50
— 3:15 pm |
Break/Transition
to Round Robins |
|
|
|
3:15
— 4:25 pm |
Engagement
Exercise 3: Round Robins |
Mentor
Tearns |
Mondavi
Center, 3rd fl. |
|
3:15
— 3:45 pm |
Rotation 4 |
||
|
3:55
— 4:25 pm |
Rotation 5 |
||
|
4:30
— 6:00 pm |
BREAK |
||
|
6:00
— 8:00 pm |
Dinner |
All
invited |
AGR
Room, Walter A. Buehler Alumni Center |
THURSDAY, MARCH 27, 2025
|
8:00
— 8:30 am |
Continental
Breakfast |
All
participants |
Vanderhoef
Theatre Lobby, Mondavi Center |
|
8:30
— 8:35 am |
Welcome
& Daily Overview |
Course
Directors |
Vanderhoef
Theatre, Mondavi Center |
|
8:35
— 9:25 am |
Session
12: Academic Drug Discovery Vignettes |
Barbara
Slusher, Ph.D., MAS, Johns Hopkins School of Medicine |
Vanderhoef
Theatre, Mondavi Center |
|
9:25
— 10:15 am |
Session
13: Clinical Considerations in the Non— Clinical Phase of Drug Discovery
and Development |
James
Vornov, M.D., Ph.D., Johns Hopkins School of Medicine and Medpace |
Vanderhoef
Theatre, Mondavi Center |
|
10:15
— 10:35 am |
BREAK |
||
|
10:35
— 11:25 am |
Session
14: Intellectual Property |
Jeffrey
Childers, J.D., Ph.D., Casimir Jones |
Vanderhoef
Theatre, Mondavi Center |
|
11:25
am — 12:15 pm |
Session
15: Industry Partnerships and Newcos: What They Are and How to Make Them
Happen |
Matt
Tremblay, Ph.D., Blackbird Laboratories; Blackbird BioVentures |
Vanderhoef
Theatre, Mondavi Center |
|
12:15
— 1:15 pm |
LUNCH
& Responsible Conduct of Research Exercise 2 |
Mentor
Teams |
Mondavi
Center, 3rd fl. |
|
1:15
— 1:20 pm |
Transition
to Round Robins |
||
|
1:20
— 2:30 pm |
Engagement
Exercise 4: Round Robins |
Mentor
Tearns |
Mondavi
Center, 3rd fl. |
|
1:20
— 1:50 pm |
Rotation 6 |
||
|
2:00
— 2:30 pm |
Rotation 7 |
||
|
2:45
— 3:05 pm |
Meet
& Walk to Arboretum |
All
invited |
Meet
outside Mondavi Center at 2:45 pm |
|
3:10
— 4:10 pm |
Guided
Tour — Arboretum |
All
invited |
UC
Davis Arboretum |
|
4:30
— 6:00 pm |
BREAK |
||
|
6:00
— 8:00 pm |
Dinner |
All
participants |
AGR
Room, Walter A. Buehler Alumni Center |
FRIDAY,
MARCH 28, 2025
All Friday activities take place at King Hall, UC Davis Law School
|
7:30
— 8:00 am |
Continental
Breakfast |
All
participants |
Hallway
outside Room 1001, King Hall |
|
8:00
— 8:15 am |
Introduction
to Presentations |
Course
Directors |
Room
1001, King Hall |
|
8:30
— 11:30 am |
Engagement Exercise 5:Student Presentations (See Presentation Schedule handout or course website) |
Mentor
Teams |
Rooms
1320, 2040, 2320, 2360, King Hall |
|
11:30
am — 12:00 pm |
Conclusion: Where do we go from here? (Course evaluation; survey) |
Course
Directors |
Room
1001, King Hall |
|
12:00
pm |
Course
Adjourns & Lunch (pick up box lunch) |
|
Hallway
outside Room 1001, King Hall |